Enhancing equine tendon repair: evaluating the synergistic effects of mesenchymal stromal cells and hyaluronic acid in a collagenase-induced injury model

This research project aims to enhance the treatment of common tendon injuries in horses, a prevalent issue causing economic losses in equine sports. Despite various treatments, there’s a crucial need for more effective solutions. The study focuses on comparing the impact of Mesenchymal Stromal Cells (MSCs) alone to a combination of MSCs and Hyaluronic Acid (HA) in a superficial digital flexor tendon injury model. By understanding the cellular and molecular responses, the research intends to provide insights into improving tendon healing. The experiment involves creating injuries in horses, assigning them to different treatment groups, and analyzing tissue responses over time. The anticipated outcome includes valuable advancements in equine tendon care, potentially extending the athletic careers of horses and reducing economic challenges on the equine industry. The partner organization involved stands to benefit from increased knowledge and potential innovations, contributing to enhanced horse health and performance.

Faculty Supervisor:

Judith Koenig

Student:

Partner:

eQcell

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

University of Guelph

Program: