Sequence comparison of SARS coronavirus 2 (SARS-CoV-2) outbreaks in mink occurring in North American/Canadian- and Danish farmed mink, and investigation into the post infection the antibody response

Aim of the study:
The aim of this study is to compare the SARS-CoV-2 sequencing data available from the north American/Canadian SARS-CoV-2 outbreaks in mink to the Danish SARS-CoV-2 outbreaks in mink, and compare genetic similarities. Moreover, a secondary aim is to investigate the antibody response in relation to SARS-CoV-2 outbreak in Canadian mink to evaluate the specificity and duration of the antibody response.
Methods:
North American/Canadian and Danish SARS-CoV-2 sequences available in NCBI GenBank will be compared, to investigate mutations occurring over time. In addition, information of the farm and time of sampling will be included, when available. Moreover, 20 serum samples from ten North American/Canadian farms having a history of previous SARS-CoV-2 outbreaks will be sampled and subjected to ELISA testing and virus neutralization tests.

Faculty Supervisor:

Younes Miar

Student:

Partner:

University of Copenhagen

Discipline:

Life Sciences

Sector:

Education

University:

Dalhousie University

Program: