This project addresses the need for clear baseline data of infections impacting avian populations, and the need for clear, thorough, and detailed reports on infection prevalence, affected avian species, and locations of infection occurrences from wildlife rehabilitation centres. Our goal is to develop clear baseline measures of three major health impacts to avian biodiversity in […]

In Brazil, malaria accounts for the highest morbidity registered in the Americas. In this country, 99.5% of the cases of malaria are registered in the Brazilian Amazon. The main goal of this research is to investigate how riberinhos experience and act upon malaria in endemic areas of Manaus and Careiro, State of Amazonas, Brazil. This […]

Parkinson’s disease (PD) is a devastating brain disorder accompained by the death of dopamine-producing neurons. Aging is the main risk factor for PD, but early-onset forms also exist and are often linked to mutations in PRKN gene, which encodes for a cellular protein called Parkin. Evidence suggests that these mutations may perturb dopamine neuron function […]

The medical cannabis industry in Canada is at the forefront of cannabis research, yet it faces significant challenges due to the plant’s complex chemical composition, including numerous cannabinoids, terpenes, flavonoids, and other bioactive compounds. Currently, cannabis prescriptions often rely on limited clinical data, leading to inconsistent therapeutic outcomes. This project addresses these challenges by developing […]

There is a growing awareness of the role of microbes in the functioning of higher organisms. The human microbiome has now been shown to play key roles in health and physiology. Similarly, plants have had microbes, mycorrhizal fungi for example, associated with their roots since they colonized the land. It is becoming clear that there […]

The proposed research project is a Phase 1 clinical trial looking at the safety of fenretinide, a molecule based on the structure of vitamin A, on patients with a disease called cystic fibrosis. Fenretinide has been shown in our laboratory to help cystic fibrosis mice by lowering molecules involved in inflammation and increasing the levels […]

Severe sepsis strikes young and old alike with an increasing incidence of >75,000 per year in Canada at a cost of $40,000 per patient. In 40% sepsis is complicated by low blood pressure and organ failure with a mortality rate of 30-60%. The number of deaths due to severe sepsis and septic shock is greater […]

Patients with chronic obstructive pulmonary disease (COPD) often experience adverse health outcomes including COPD exacerbations and cardiovascular events. These events impose a significant economic burden on the healthcare system and lead to impairment of patients’ wellbeing. This project aims to develop a clinical prediction model (CPM) to predict the risk of COPD exacerbations and cardiovascular […]

This study proposes to evaluate the quality of movement in patients with low back pain using a novel device. We are going to measure and compare the movement of people with back pain to that of healthy people. In addition, we plan on correlating the psychological factors associated with low back pain to tissue pathology. […]

Les athlètes d’endurance ont recours à l’entraînement par intervalles de haute intensité afin de maximiser l’éventail des adaptations physiologiques qui sous-tendent la performance aérobie. Cependant, il existe une grande variabilité de réponses à l’entraînement selon les caractéristiques physiologiques des athlètes et de leur sexe, et l’identification des séances d’entraînement bénéfiques à toutes et tous est […]

Light can be used to control biological processes in living cells, a technique called optogenetics. Originally developed to control neural activity, optogenetics has been expanded to control protein interactions and gene expression with a high degree of spatial and temporal control. This has opened exciting possibilities in developmental biology and tissue engineering. However, current optogenetic […]

L’aquaculture est une industrie à forte croissance à l’échelle globale mais qui tarde à se développer au Québec. L’élevage de nouvelles espèces pourraient aider à diversifier et stimuler cette industrie. Le loup tacheté est une espèce marine d’eau froide qui possède d’excellentes caractéristiques pour l’élevage commercial. L’étape de reproduction est maîtrisée, mais le succès d’incubation […]