Project A: Feasibility study for the use of saliva samples to understand the Pharmacokinetic (PK)/Pharmacodynamic (PD) relationship for a developmental therapeutic

HyperMabs is a protein engineering company focused on the development of therapeutics for diseases with high unmet need including Covid-19. The role of the Translational Science Team is to discover and develop biomarkers that indicate pharmacodynamic response to the company’s therapeutics as well as support the relevance of the targeted biological pathways in diseases of […]

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Project B: Support indication selection for HyperMabs’ developmental therapeutic by building translational rationale for target prevalence.

HyperMabs is a protein engineering company focused on the development of therapeutics for diseases with high unmet need including Covid-19. The role of the Translational Science Team is to discover and develop biomarkers that indicate pharmacodynamic response to the company’s therapeutics as well as support the relevance of the targeted biological pathways in diseases of […]

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Innovative tools to improve knee health and predict an athlete’s risk of anterior cruciate ligament (ACL) injury

Anterior cruciate ligament (ACL) injuries are one of the most frequent injuries among athletes. Currently, the only way to predict an individual’s risk of incurring an ACL injury is through prohibitively expensive motion analysis laboratories. There is a critical need to develop novel tools that improve knee-health and are well-received by the athletic community. This […]

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Determination of phenolic content and bioactivity in the Winecrush puree developed from a grape pomace

The evidence provided by epidemiological and clinical studies is persuasive of protective effects of fruit and vegetable intake in chronic disease. The edible parts of many fruits and vegetables are a rich source of dietary compounds that impact human cell functioning. Those bioactive compounds are often lost during food production and processing. For example, skin […]

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Synthetic biology constructions toward bacteria-mediated cancer therapy

Development of selective drug delivery agents that target tumor cells with minimal toxicity to normal tissues is a major challenge in cancer therapy. Non-toxic bacteria can be used to target solid tumors because, within a patient’s body, they can only be active at a tumor site (where oxygen levels are pathologically low). Prior attempts at […]

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Adaptive Biofilm-Based apparel (ABBA)

Consumers are becoming increasingly interested in “smart” clothing with advanced properties that can enhance their comfort and performance. The next-generation of “smart” textiles can be fabricated by integrating living cells into the textiles that make up our clothing. For users of fitness apparel, living cells can endow clothing t-shirts or yoga pants with the ability […]

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Assessing the acoustic and physical disturbances of marine traffic on the Northern Resident Killer Whales in the Robson Bight Michael Bigg Ecological Reserve

The northern resident killer whale (NRKW) population off British Columbia’s coast is considered ‘threatened’ within Canada. Recent studies have shown that NRKWs face many threats, with a key stressor being the negative interaction with commercial and recreational vessel traffic. The Robson Bight Michael Bigg Ecological Reserve is a marine protected area in Johnstone Strait, east […]

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