Design and Prototype Validation of a Bioabsorbable Flow Diverting Stent

An aneurysm is a balloon off a blood vessel in the brain, that could potentially bleed resulting in devastating consequences for the patient. Brain aneurysms a common, and are present in up to 7% of the general population. Traditional treatment of complex brain aneurysms involves placing a metal “flow-diverting” stent across the neck of the […]

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Role of Autophagy in Neurogenesis during Stroke Recovery

In the late 1990s, scientists made the remarkable discovery of neurogenesis in the adult human brain, defined as the process of new neurons being formed from neural stem cells. This was a remarkable discovery since it raised hope that we can replace neurons that have died following a stroke. Thus many researchers are trying to […]

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Neural correlates of aphasia therapy after stroke

The objective of the proposed project is to better understand how the brain recovers language functions after a stroke. We want to determine what the changes are in the brain of a person who has had a stroke when they can say more words after treatment for their speaking difficulties. We want to know if […]

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Investigation of Cytokine Signaling in the Immune System

We combine quantitative experimental measurements of immune cells with mathematical models to systematically study the body’s anti-viral response. In particular, we are looking at how immune cells communicate with each other to coordinate an immune response. We want to understand how biochemical reactions in the cell can be used to process the complicated pattern of […]

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Investigating Early Land Plant Cuticular Wax Biosynthesis

The plant cuticle is an essential extracellular structure required for plant survival on land. It forms a seal over the aerial plant surfaces providing protection against biotic and abiotic stress. It controls water exchange between the plant and its environment and reduces the risk of infection and herbivory. Cuticle structure, composition and biosynthesis are well […]

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Vers la production de protéines animales durables : optimisation de l’utilisation de l’azote alimentaire chez le porc et le poulet

L’objectif général de ce projet est de réduire les apports en protéine brute (PB) en optimisant son utilisation par les animaux, en ajustant, aussi précisément que possible, les apports aux besoins des animaux afin d’éviter une réduction des performances lors de la baisse de PB. Cela permettra de réduire les rejets d’azote, mais pourrait également […]

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Analyzing neuroprotective properties of Lactobacillus rhamnosus HA114 in models of age-dependent neurodegeneration

Our aging population is burdened by decreased health and an increased risk of disease, including for many age-dependent neurodegenerative disorders like amyotrophic lateral sclerosis and Alzheimer’s disease (AD). There are no cures for these conditions, and according to the United Nations the number of people affected may double by 2040. Using simple genetic models of […]

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Adapting Kinematic Profiles to Apraxia Patients

We want to better understand the problems that arise from apraxia, a movement disorder that may result after stroke. These individuals experience difficulty in producing skilled or learned movements, and have difficulties doing activities of daily living. As a result we want to record their movements using portable sensors to have more objective measures of […]

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The Safety, Efficacy, and Tolerability of Microbial Ecosystem Therapeutic-2 in People with Major Depression and/or Generalized Anxiety Disorder

The gut-brain axis is being heavily explored in current neuropsychiatric research. Evidence has shown considerable individual variability in bacterial content of the gut microbiota, which is hypothesized to influence brain function. Preclinical and clinical research examining this relationship suggests that fecal microbiota transplant (FMT) may aid in improving depression and anxiety symptoms by recolonizing the […]

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Evaluating Skill Transfer Between Canadian and Global South Midwifery Associations

The Canadian Association of Midwives (CAM) implements global programs in Africa and the Caribbean, building midwives’ technical skills and strengthening the capacity of midwifery professional associations in our partner countries. CAM seeks two researchers first to assess current best practices in skills and knowledge transfer activities (particularly the transfer of healthcare skills) and civil society […]

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Determining the mechanisms implicated in the development of preeclampsia

Preeclampsia is a pregnancy-associated disease where women develop high blood pressure and protein in their urine. It is the leading cause of mother and foetus mortality and morbidity. However, we have yet to identify its specific cause as well as methods for early detection and prevention. Women who have high-blood pressure are more at risk […]

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