Direct lineage reprogramming (DLR) is the newest advance in the field of cellular reprogramming. It is the forced conversion of one mature cell type to another, without the need for a pluripotent intermediate, directly at the site of injury or disease. We have developed DLR technology to convert astrocytes into new oligodendrocyte lineage cells (iOLCs) […]

Protvac aims to unlock the dark proteome against cancer by uncovering novel therapeutic targets. Studies show the non-coding DNA (dark genome) that has been thought to be irrelevant till now can translate into previously unannotated targets. In one proteogenomic study of human tumors, nearly 90% of tumor-specific antigens came from non-coding regions areas that standard […]

As the demand for surgical interventions and the complexity of procedures increase, the need for intelligent, scalable solutions for care automation is more urgent than ever. We aim to translate cutting-edge research in neurorehabilitation and functional assessment technologies into a new generation of medical analytics systems. Capable of extracting meaningful insights from surgical procedures, we […]

Chronic diseases incur a significant socio-economic cost to both patients and the health care system. Physicians must continuously monitor and modify therapies to best meet the patients’ changing requirements, often requiring regular health care visits for specialized testing. Hydroxychloroquine (HCQ) is a disease-modifying antirheumatic drug often prescribed to patients with chronic inflammatory diseases such as […]

Precision Social Prescribing (SRX) closes the loop from community organizations to referring clinics with a web app to monitor clients’ wellbeing and the effective implementation of SRX programs. Precision SRX provides participatory geospatial information system (PGIS) Software as a Service (SaaS) and thrives on a dense network of users in a locality. Precision SRX requires […]

Over 23,000 men were diagnosed with prostate cancer (PCa) in Canada in 2020. Focal therapy uses high energy focused heating delivered via a laser fiber to destroy the tumour and has shown promising results in controlling prostate cancer. Magnetic resonance imaging (MRI) allows the surgeon to distinguish the cancerous tissue from healthy tissue, better customize […]

Neuractas Therapeutics is a Canadian pharmaceutical company that is developing novel agents for neurological indications. Neuractas has developed neur-04 for epilepsy, this agent is a reformulation of an existing drug that has demonstrated strong clinical anticonvulsant activity in the most difficult-to-treat cases of epilepsy. Often people with epilepsy have to try several different medications before […]

The intern will undertake the development and evaluation of a novel gene-edited immune cell therapy for the treatment of different cancer types. The cancer immune cell therapy is a hot and rapidly growing field that has yielded success and clinically meaningful benefits for the treatment of certain cancers. Many of these successes have been with […]