Synthesis of ligand-lipid conjugates to enhance intracellular delivery of siRNA-lipid nanoparticles to non-liver tissues in vivo

  One of the most important biological advances made in the last 10 years has been the discovery of RNA interference (RNAi) and the ability of short pieces of RNA (siRNA) to inhibit protein synthesis with remarkable specificity and potency.  This technology holds great promise as a new generation of highly active drugs with low […]

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