Long-term effects of tillage, crop rotation, cover crop, and fertilizer nitrogen on soil organic carbon and total nitrogen storage – Year two

Soil organic matter and soil organic carbon (SOC) are the important drivers of soil health. Although winter wheat and red clover have improved the soil health and system resiliency in Ontario (Gaudin et al., 2013), little is known on how quickly changes to soil health can be made and under which management systems. With Federal […]

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Development, implementation and validation of new anti-E6 therapeutics for the treatment of HPV-associated cancer

Human papillomaviruses (HPVs) are responsible for almost all cervical cancers. Current treatment available relies on chemo- or radiation-therapy or surgery. These methods have several side-effects with high morbidity and survival of just ~ 70%. Our lab, therefore, develops a more patient-centered approach based on targeting the viral E6 protein, the main culprit of carcinogenesis in […]

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Development, implementation and validation of new anti-E6 therapeutics for the treatment of HPV-associated cancer – Year two

Human papillomaviruses (HPVs) are responsible for almost all cervical cancers. Current treatment available relies on chemo- or radiation-therapy or surgery. These methods have several side-effects with high morbidity and survival of just ~ 70%. Our lab, therefore, develops a more patient-centered approach based on targeting the viral E6 protein, the main culprit of carcinogenesis in […]

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Promoting economic development and vitality of rural communities in Ontario

Many rural regions do not have a sufficient labour force providing the skills that rural businesses need. Many job vacancies go unfilled or are filled by less than ideal candidates. This research looks at strategies to attract and retain the workers that Ontario rural communities need to generate economic development and vitality. By engaging local […]

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Fibre in IBD: Feeding Our Microbes vs. Fuelling Inflammation

While studies show that dietary fibres are beneficial in many diseases, they are not digested or absorbed directly by the host, but rather fermented by gut microbes. Fermentation byproducts (mostly short-chain fatty-acids; SCFAs) are responsible for health benefits. Only select inflammatory bowel diseases (IBD) patients benefit from fibres; many patients report sensitivity to high fibre […]

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Fibre in IBD: Feeding Our Microbes vs. Fuelling Inflammation – Year two

While studies show that dietary fibres are beneficial in many diseases, they are not digested or absorbed directly by the host, but rather fermented by gut microbes. Fermentation byproducts (mostly short-chain fatty-acids; SCFAs) are responsible for health benefits. Only select inflammatory bowel diseases (IBD) patients benefit from fibres; many patients report sensitivity to high fibre […]

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Complementary and competitive interactions between wild and managed bees

A diversity of native bee species inhabit agricultural and urban landscapes and can be more effective pollinators than the widely employed European honey bee. However, honey and wild bee communities often overlap, which means these bees compete for the same floral resources. Studies of competition between wild and managed pollinators are limited due to methodological […]

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Complementary and competitive interactions between wild and managed bees – Year two

A diversity of native bee species inhabit agricultural and urban landscapes and can be more effective pollinators than the widely employed European honey bee. However, honey and wild bee communities often overlap, which means these bees compete for the same floral resources. Studies of competition between wild and managed pollinators are limited due to methodological […]

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Development of a wireless mini-microscope for the study of brain function

In the last years imaging using miniature microscopes (mini-microscopes also called mini-endoscopes) has become a method of choice for the understanding of activity at the cellular and network levels in different brain regions, in freely behaving animals. However, mini-microscopes are connected with wires to other devices, which largely alleviate the use of these imaging systems […]

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