Development of Neurotherapeutics from Lead Candidates

There is a critical need to develop new therapeutics for the treatment of chronic pain. In this partnership between Zymedyne Therapeutics and the Derksen Research lab at the University of Calgary, we will work to develop lead hit compounds to leads that can be put forward as clinical candidates. As many existing pain therapeutics, such […]

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Accessible Communications of the Needs of Persons with Disabilities

Building codes are often written in complex legal language, making them difficult to understand. While diagrams can help, they often lack standardization and fail to convey the intent of the requirements. To help architects, engineers, contractors, and inspectors to understand the intent and specifics of requirements, we aim to develop a set of best practices […]

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Simulation of cerium dissolution and interaction with the catalyst-ionomer interface in fuel cells

Polymer electrolyte fuel cells are a key technology in the race against climate challenges, and while commercial applications are increasingly common, challenges remain in cost, performance, and durability. Most of the issues that prevent full commercialization affect the catalyst layer, the region where the power-generating electrochemical reactions take place, like the oxygen reduction reaction. This […]

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Implementing and Assessing the Pyramid Model for Promoting Socio-Emotional Competence in Early Childhood Educators: An Action Research Project in Prince Edward Island

This innovative project aims to implement and evaluate the Pyramid Model for Promoting Social Emotional Competence in Infants and Young Children framework (PM) for promoting social-emotional competence in the early learning and childcare sector (ELCC) in Prince Edward Island (PEI), Canada. The project engages 18 Early Childhood Educators (ECEs) and 10 coaches across PEI over […]

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LastMile AI Project

Our research aims to address the trustworthniess, scalability and interpretability of LLMs in the RAG enviroment by generating not only novel academic insights but also practical technology that helps enterprise AI users better understand, evaluate, and debug. By achieving a deeper, theoretically and empirically grounded understanding of how LLMs behave within RAG systems, we seek […]

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Design ethical AI systems for nautical crime database

The Food and Agriculture Organization of the United Nations reports that illegal, unreported, and unregulated (IUU) fishing accounts for as much as 26 million tonnes of fish each year, with a value ranging from $10 to $23 billion USD. Despite its significance, there is a notable lack of comprehensive international databases on nautical crimes, including […]

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Novel Specific Coagulant/Flocculant Pairs for Mineral Tailings Treatment

Water management and treatment of mineral tailings and oil sands tailings are becoming critical challenges for the sustainable development of natural resources exploration. Reclamation of these tailings is challenging due to a solid phase composed mainly by very fine particles and many other chemicals. With these characteristics, the tailings form a very stable colloidal system […]

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In vivo testing of LNP-mRNA therapeutics in an animal model of Gaucher Disease

Brain disorders affect 10% of Canadians, however few treatment options exist for these devastating diseases. We have extensive understanding of their causes, but translation to treatment has been difficult. For example, many natural proteins have been identified to hold significant therapeutic promise, but getting these proteins to the brain has been a longstanding challenge. Our […]

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Enhancing Concussion Assessment Accuracy Using Kinarm Robotic Platform: A Statistical Approach to Evaluating Neurological Deficits in Athletes

The project aims to improve how concussions in athletes are detected by using the Kinarm robotic platform, which measures sensory, motor, and cognitive functions. By analyzing data from healthy and concussed athletes, the project will develop a more accurate method for identifying neurological issues after a concussion. This will help the partner organization enhance athlete […]

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Immersive Control Centre for Space Mission Management and Collaboration

Our project aims to revolutionize space mission management by developing an immersive control centre that harnesses advanced virtual and augmented reality technologies. This innovative center utilizes digital twin technology to create accurate 3D models of space environments and vehicles, allowing operators to interact with missions as if they were physically present. This approach significantly enhances […]

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“But…I don’t feel recovered”: Enhancing concussion care in partnership with youth who have experienced ‘prolonged recovery’

Youth concussion rates are rising nationally. Accordingly, efforts are being made to enable the recovery of injured youth. However, little is known about what recovery ‘is’ from the perspective of youth (eg, the care youth need to support recovery). This represents a major gap in knowledge of youth concussion. This research project will partner with […]

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