Advanced Simulation Methods for a Next Generation Computational Fluid Dynamics Solver Year One

Computational Fluid Dynamics (CFD) is a branch of fluid mechanics that is focused on using numerical methods to solve and analyze practical engineering problems involving fluid flow. The purpose of the proposed research project is to develop novel simulation methods directed at applications in sensitivity analysis and design optimization. Sensitivity and optimization studies are becoming […]

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Development of Novel Methods for the Automated Extraction of Lipid-Soluble Compounds Year One

Current analytical methods for the extraction of lipid-soluble compounds (fatty acids, cholesterol, antibiotics, pesticides, vitamins) are costly and time-consuming. Recently, we have assessed a novel patent-pending “kit” method for extracting fatty acids and cholesterol from food and tissues with great success. We propose to continue testing this method for extraction of lipid-soluble vitamins, pesticides and […]

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Action spectra characteristic of typical and potentially new challenge organisms used in polychromatic UV reactor validation Year One

Trojan Technologies provides UV-based technologies for water, wastewater and reuse wastewater treatment. This proposal is directed towards optimizing and developing the validation protocols for UV systems provided by Trojan. The study results will expand Trojan’s ability to provide more holistic and sustainable reactors for water/wastewater treatment as well as expand the polychromatic UV market. From […]

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Multifunction system for measuring endothelial cell remodeling under laminar and turbulentpulsatile flow related to heart disease Year One

A London-based company, Novel Cardiovascular Systems Inc, has developed a unique multifunction system for measuring endothelial (arterial wall) cell remodelling under different types of laminar, turbulent and intermittent pulsatile flows that are associated with the onset and development of heart disease, notably atherosclerosis (narrowing of the artery). In order to accelerate the product to market, […]

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Stochastic Control in Network Coding Enabled Wireless Systems Year One

Network stochastic control is considered as a primary goal in the design of emerging wireless networks. One of the objectives in the stochastic control of wireless networks is to enable crosslayer designs to achieve stochastically optimal resource allocation in the physical and MAC layers. Different stochastic performance criteria can be considered in the optimal control […]

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Combined Building Integrated PV/Thermal (BIPV/T) Collector with Two-stageVariable Capacity Air Source Heat Pump for Net-Zero Energy Building Applications Year One

Building Integrated Photovoltaic/Thermal (BIPV/T) systems are arrays of photovoltaic panels integrated into the building envelope facades and roofs that produce electricity and incorporate the additional function of recovering useful thermal energy. The energy can be used for space, domestic water heating or air conditioning. Recuperating heat from the BIPVjT system improves electrical efficiency and reduces […]

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Aptamer-facilitated Virus Shielding (Apta?ViSh) Technology and Aptamer-facilitated AntivirusShielding (Apta-AntiviSh) Technology to extend the in vivo action of oncolytic viruses. Year One

This project aims to develop an aptamer?based technology to enhance the in?vivo survival of oncolytic viruses and thus the efficiency of virotherapy. Oncolytic viruses (OVs) can selectively replicate in tumor cells, leading to lysis of the tumor. OVs are particularly effective against metastatic cancers, which are especially difficult to treat conventionally. However, OVs can be […]

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Development of an Electrodynamic Simulation Toolbox for Nanophotonics

Finite Difference Time Domain (FDTD) simulations allow researchers to model complex devices and systems based on integrated micro/nano structures. The electrodynamic behaviour predicted by FDTD simulations match very well with the real physical systems, which significantly accelerates the development of novel devices. However, there are limitations in existing FDTD techniques to model metal nanoparticles on […]

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