Computational study of the effect of gene deletion (synthetic lethal) on cellular growth in pathogenic organisms

Infectious diseases kill millions of people each year. For example, according to World Health Organization’s estimate, 10 million people contracted tuberculosis in 2017 resulting in 1.6 million deaths, which is approximately one death every twenty seconds . Increasingly, the pathogenic organisms, responsible for these diseases, are evolving to be resistant to drugs already in use […]

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A Novel Approach to Total Shoulder Arthroplasty using Intraoperative Manufacturing for Patient Specific Guides

Total Shoulder Arthroplasty (TSA) is a surgical procedure to restore overall comfort and function of the affected shoulder. Traditional methods of TSA are highly invasive, and result in 68% of patients developing future complications post operation. Therefore, F. Rodriguez & J. Giles developed two paradigm shifting surgical methods to reduce the invasiveness of the surgery […]

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