Apelin Analog Therapy as an Innovative Treatment for Cardiovascular Diseases

Apelin, an innate peptide, is a critical component of the apelin pathway, which is responsible for regulatory mechanisms of the cardiovascular system. Apelin is downregulated in patients with cardiovascular disease, therefore limiting the cardioprotective potential of the pathway. This project focuses on the optimization of a biological analog, able to withstand enzyme degradation with improved […]

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Validation of SIMBA capsules for small intestine sampling

The aim of this research and development project for the intern student is to assist in validation tests (both in-vitro and in-vivo) of a GI sampling capsule device being developed by the organization and translate the testing results and the new knowledge to technical documents for the potential customers and partners of the organization. In-vitro […]

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Dynamics of T-cell recruitment and polarization in inflammatory skin diseases

Psoriasis is an auto-immune disease in which the T-cells (type of blood cells involved in fighting infection) mistakenly attacks the cells within the body leading to formation read scaly patches or plaques on the skin. Plaque Psoriasis that occurs in 80-90% of the patients is associated with anxiety and depression that negatively affects patients social […]

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Development of Technologies and Methods for Metabolite collection and processing

Metabolomics is an emerging field of research that provides insight into health and disease by studying the levels of various small molecules (metabolites) in the body. In this project, we are developing new tools that will improve and standardize methods for collecting and stabilizing fecal samples for metabolomics studies based on the analysis of fecal […]

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Impact of garlic supplementation and Residual Feed Intake profile on the occurrence of liver abscesses in feedlots

Feed efficient finishing cattle with none or less severe cases of liver abscesses (LA) will improve the competitiveness and sustainability of the beef industry. The antimicrobial properties of garlic have not been evaluated towards mitigating the severity of LA. Studies evaluating the association between feed efficiency and LA and the integration of emerging feeding strategies […]

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Pipeline defect matching based on data from consecutive in-line inspections

The integrity of energy pipelines is managed using information obtained from in-line inspections, which are periodically performed non-destructive inspections of the pipe wall to detect and size defects like corrosion, cracks, and dents. The coordinate systems for referencing the locations of the detected defects varies from inspection to inspection. It is therefore necessary to align […]

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Exploring the economic impacts of Human-Centered Design in the context of a non profit organization

This exploratory research will seek to answer the primary question generally asked by many industry professionals- “how to evaluate the economic assessment of projects (using Human Centered Design (HCD) philosophy)”. This research will explore how to create an ROI/cost benefit analysis tool to measure economic impacts of the specific type of projects. This report will […]

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Probiotics in pediatric neurodevelopmental disorders

Autism spectrum disorder (ASD) is a kind of chronic neurodevelopmental disorders that detrimentally affect the behavior and development in children. There is a tight need for efficient treatment. Scientific evidences have shown that the gut microbiota as well as their metabolites may mediate the responsiveness to changes in diet (e.g. ketogenic diet). However, clinically relevant […]

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The development and feasibility/acceptability testing of an online mind-body wellness program for primary biliary cirrhosis

Persons with primary biliary cholangitis (PBC) have high rates of liver disease-related symptoms and poor health-related quality of life – amongst the lowest of all chronic liver diseases. Patients and the Canadian PBC Society have identified the need for self-care tools to manage symptom burden. Building upon a previously developed online wellness program for inflammatory […]

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Decolonization, engagement and multi-sectoral collaboration from an urban Indigenous perspective.

The research project will look at how EndPoverty Edmonton has engaged with the diverse Indigenous population that lives in Edmonton on their interests and perspectives on eliminating poverty. Indigenous peoples and communities continue to experience social and economic inequality as compared to other Canadians. Their social and economic inequality can be linked to the impacts […]

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Acoustic Emission Testing of Fibers Exposed to Different Environmental Conditions

This research project investigates methods for detecting damage and breakage in fibers used in fiber-reinforced polymer composite pressure piping. Of primary interest is Acoustic Emission (AE) technology to isolate and identify damage types and corresponding AE features for fiber reinforcement rupturing when exposed service loads and different environmental conditions. Sound signals produced by fiber rupture […]

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