Development of 3D culture reagents and scoring systems for assays of normal andmalignant epithelial stem cells

The overarching objective of this proposal is to develop and validate a new, robust and reproducible 3D culture system that supports the clonal growth of primary sources of normal and malignant human epithelial cells and that is suitable for commercialization by STEMCELL Technologies who will partner in its development. The work will systematically address 3 […]

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Biophysical Characterization of Novel PARP Inhibitors

PARP inhibitors are an FDA-approved treatment for breast, ovarian and prostate cancers. This project aims to develop 3 new classes of PARP inhibitors, 2 of which can target multiple pathways with a single drug, helping to prevent resistance to the PARP inhibitors and enabling the combination of 2 drug treatments without the added side effects […]

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Development of tests to assess GDL stability during MEA production

Mercedes-Benz Canada Inc. is engaged in producing fuel cell stacks for automotive applications. The plant in Burnaby BC is the exclusive fuel cell manufacturer for Mercedes-Benz worldwide (marking the world’s first large-scale production facility for automotive fuel cells.) The Mercedes-Benz Fuel Cell Division (MBFC) has shown interest in active collaborations with Canadian universities and research […]

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Successful schools: Building a better measure of success

There are two interconnected processes required for this project to succeed: a process of consultation and engagement of the public and stakeholder groups, and the more technical development of measures. Both areas involve key methods for applied research and knowledge mobilization within the social sciences. CONSULTATION AND ENGAGEMENT To succeed, the Broader Measures project must […]

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From Waste to Hydrogen: Assessment of Alternative Hydrogen Production Processes

With the Focus around the world shifting to net-zero emissions as a solution to the climate crisis, countries are stepping up with hydrogen strategies and committing large amounts of funding to make hydrogen a reality. However, the main problem remains: On the supply side, hydrogen currently cannot be offered competitively with Diesel/NG prices, and on […]

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Molecular You – Clinician Review Module UX Design

This project is a collaboration between the Emily Carr Institute of Art and Design and Molecular You. Molecular You are a health-tech start-up on a mission to help everyone live longer healthier lives using a new type of digital health experience that can spot early warning signs of chronic disease and tell you exactly what […]

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Disinfection efficacy of Far-UVC light in a healthcare facility

UV light is known for its antimicrobial properties. In this project, we expect to use a proprietary lamp which will provide a specific light that will target bacterial, fungal and viral strains commonly found in health care facilities. Results of the project will have a direct impact in the sterilization of areas with a high […]

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Creating He- using H- ion source beam on He0

Metals, and particularly alkali metals, are contaminants in silicon wafers used to make computer chips and power electronics devices [1,2,3]. The movement of contaminating ions in the SiO2 under the influence of an applied voltage across the oxide causes the electrical characteristics of the transistor, such as the threshold voltage, to change [4]. This is […]

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Neural network optical characterization of accreting black holes

Astronomers have long used optical spectra (detailed wavelength-specific measurements of light) to categorize galaxies. A galaxy’s spectrum encodes information about its constituent stars, gas, and dust and its central super-massive black hole (SMBH). SMBHs that are actively accreting, known as active galactic nuclei (AGN) are of particular interest to astronomers interested in SMBH physics and […]

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Minpraxis Tester signal processing automation and validation

The most energy intensive component of mineral processing is comminution (crushing and grinding), consuming, on average, about 50% of the total electric energy of a mine site. To optimize and thereby improve the energy performance, accurate measurement of the ore hardness is critical. The proposed study is aimed at developing a new test apparatus that […]

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