Design and screen novel cell-penetrating peptides intracellular delivery of proteins

This project focuses on improving the delivery of a therapeutic protein called ribonuclease (RNP) into cells, which could help treat certain genetic diseases. The challenge with current delivery methods is that the proteins often have trouble getting inside the cell and reaching the nucleus, where they are most needed. To address this, Sinedore Bioscience, in […]

Read More
Riverine feature extraction from high-resolution imagery

Physical infrastructure designed and developed to enable this growth has been in place for 50 years or more, and an increasing proportion has reached the end of its design life. Taking dams for example, while the Canadian case is less well documented, 85% of U.S. dams will be >50 years old by 2020. In particular, […]

Read More
Development of multifunctional and sustainable hybrid composites reinforced with asphaltene-based carbon fibers and natural fibers

The project will develop a multifunctional and sustainable hybrid thermoplastic composite reinforced with asphaltene-based short carbon fibres (CF) and continuous natural fibres. The fibre-matrix interface of the hybrid material will be characterized through tensile and fracture toughness tests and its multifunctionality in terms of enhanced electrical conductivity and electromagnetic interference (EMI) shielding will also be […]

Read More
GELP Leadership Camps – Marketing and Business Development

The Global Emerging Leadership Program (GELP) is addressing a crucial gap in providing early leadership, career planning, and educational guidance to high school students (Grades 10-12). The problem GELP aims to solve is the lack of structured, accessible programs that support students in making well-informed decisions about their future education, career paths, and scholarship opportunities. […]

Read More
Effets des mécanismes génétiques et écologiques sur l’évolution de la dormance des graines dans une méta-population

Les traits d’histoire de vie, ce sont des traits primordials qui déterminent la fécondité et la survie. La génétique, l’environnement et leurs interactions les affectent de grande ampleur. Mon projet met en évidence des traits d’histoire de vie des plantes : la dormance et la taille des graines. En utilisant des données climatiques, j’ai développé […]

Read More
High throughput tissue distribution study of polymer-lipid nanoparticle formulations using DNA barcode technologyy

Our project aims to develop polymer-lipid hybrid nanoparticles (pLNPs) to enhance gene delivery to cells throughout the body, addressing two major challenges: ineffective release of genetic material inside cells and limited targeting of non-liver tissues. By incorporating a pH-sensitive material, our pLNPs are designed to improve the release of their genetic cargo within cells while […]

Read More
Framework for advancing mini forests in Canada

Despite the proliferation of mini forests across Canada, and the financial commitment to increase canopy cover in urban areas, there is very little systematic research conducted on the range of benefits and the effectiveness of mini forests. For the MITACS Accelerate we envision involving an undergraduate student as a project intern to support the development […]

Read More
Examining the influence of PAS-induced LTP delivered over the visual cortex and cerebellum on motor performance and functional connectivity post stroke.

Learning a motor task is dependent on many cortical regions. As a skill is learned, changes take place within the circuitry of the brain to optimize efficiency of the movement execution. Following stroke, motor deficits in the upper extremity are common, emphasizing the need for intact skill learning to reacquire motor function. Advancements in rehabilitation […]

Read More
Comparative Analysis of Unregulated Drug Supply Trends and Drug Checking Strategies in British Columbia and France

The ongoing illicit drug poisoning crisis in Canada has resulted in over 40,000 deaths since 2016, with British Columbia being the province hardest hit. The crisis is largely driven by the presence of potent fentanyl analogues in unregulated drugs, leading to this significant rise in overdose deaths. In contrast, Europe, including France, has not experienced […]

Read More