A Bayesian pharmacokinetics integrated phase I–II design to optimize dose-schedule regimes for multi-level multi-graded outcomes

Cancer treatment requires a precise understanding of how drugs work at different doses and schedules. This research project aims to develop an advanced method for designing clinical trials for early-stage cancer beyond traditional approaches. The project will create a sophisticated statistical framework that simultaneously evaluates drug toxicity and effectiveness across multiple complexity levels while incorporating […]

Read More
Fur Seals, Nuu-chah-nulth and Pelagic Sealing in British Columbia (1860s-1910s)

In Canada in recent decades, Indigenous Peoples have been recognizing publicly their relationship with the environment as one of the fundamental features of their cultural identity. The project will show that historically Nuu-chah-nulth/marine mammal relationship was much more complex than commonly understood. While whaling is today recognized as central in their identity, history, and culture […]

Read More
Building Language-Based Tourism Opportunities in Haida Gwaii, Canada

The purpose of this project is to work with the Haida to implement a community-based tourism program to support the development and revitalization of their language. Based on the findings of a doctoral thesis undertaken with the community, the program will support culturally appropriate uses of language within tourism settings. Foundational to the program is […]

Read More
Development of mass spectrometry-based metabolomics to explore the chemical complexity of cannabis

The medical cannabis industry in Canada is at the forefront of cannabis research, yet it faces significant challenges due to the plant’s complex chemical composition, including numerous cannabinoids, terpenes, flavonoids, and other bioactive compounds. Currently, cannabis prescriptions often rely on limited clinical data, leading to inconsistent therapeutic outcomes. This project addresses these challenges by developing […]

Read More
Deep Learning Measurements to Model Ecosystems’ Response to Environmental Change

In many applications, Machine Learning (ML) predictions are used to make downstream decisions. Acting on ML predictions however can change the distribution of features that the ML model relies on for predictions. The implication is that such downstream decisions procedures implicitly expect the ML model to generalize outside of the observational distribution. Unfortunately, this is […]

Read More
Dissecting the role of PCSK9 in sepsis

Severe sepsis strikes young and old alike with an increasing incidence of >75,000 per year in Canada at a cost of $40,000 per patient. In 40% sepsis is complicated by low blood pressure and organ failure with a mortality rate of 30-60%. The number of deaths due to severe sepsis and septic shock is greater […]

Read More
Separation of sub-micron particles in flowing air streams: CFD modelling and design optimization

Classification and separation of solid particles immersed within an air stream plays a crucial role in aerosol separation, air filtration, fine particle recovery, and many other applications. Particle separators divide a mixture of different-sized solid particles in a flowing gas stream into fine and coarse streams. IMASCO Minerals produces ultrafine dry ground calcium carbonate (CaCO3) […]

Read More
Risk Prediction Modelling of Adverse COPD and CVD Outcomes in Patients with COPD

Patients with chronic obstructive pulmonary disease (COPD) often experience adverse health outcomes including COPD exacerbations and cardiovascular events. These events impose a significant economic burden on the healthcare system and lead to impairment of patients’ wellbeing. This project aims to develop a clinical prediction model (CPM) to predict the risk of COPD exacerbations and cardiovascular […]

Read More
Expanding virtual learning and teaching resources at VanDusen Botanical Gardens for formal and non-formal learning spaces.

The Vancouver Botanical Gardens Association (VBGA) is a non-profit organization that collaborates with the Vancouver Park Board to manage both the Bloedel Conservatory and VanDusen Botanical Garden. Their goal is to help people of all ages understand the importance of biodiversity and to inspire a lasting love for plants and gardens through various programs and […]

Read More
Researching strategic and business opportunities: using AI to foster animal (pet) health

Empawerpet (empawerpet.com) is pioneering the field of canine mental health diagnostics through their veterinary clinic-based biomarker testing platform. While they have established a foundation in biochemical analysis, they recognize the need to expand their diagnostic capabilities through a new AI non-invasive, accessible methods. The company is therefore interested in expanding their current clinic-based biomarker testing […]

Read More
Development of supply chain for wood pellet heating applications in the Canadian Northwest Territories

This project will explore how wood pellets can be used more widely as an affordable, sustainable heating option in the Northwest Territories (NWT). While some areas already use wood pellets, there’s potential to expand this environmentally friendly alternative to fossil fuels like oil and diesel. The research will involve gathering information, working with local communities, […]

Read More
Mind-sets at White Water West: Analysis and Instructional Intervention

This research project will investigate the attitudes and beliefs towards learning and different kinds of training programs at a company called White Water West, with the intention of then addressing any identified problem through the design, development, and implementation of learning programs and materials. This proposal is for a single internship unit of four months, […]

Read More