Brain natriuretic peptide (BNP) is an established prognostic marker for the early detection of heart failure. Elevated blood BNP levels are directly correlated to the severity of HF and decompensation. Current FDA approved immunoassays for BNP detection can only be carried out in medical laboratories or emergency rooms. Outpatient-use BNP monitors are yet to be […]

Heart Failure (HF) occurs when the heart becomes damaged or weakened. HF is an epidemic, with approximately 1 million Canadians affected. BNP is an effective diagnostic and prognostic marker for HF. There is a direct correlation between elevated concentrations of BNP in the blood and the severity of HF symptoms. The need for point-of-care monitoring […]

Our previous work has shown the promise of monodisperse phytoglycogen for many applications. However, these experiments only scratch the surface of potential uses since the chemistry of the particles (as extracted) is fixed. Nanoparticles offer very high surface areas, and glucose units are easily modifiable, thus there exist a multitude of ways to chemically modify […]

Administration of supplemental oxygen through medical air is a life-supporting measure essential for the management of severe primary respiratory conditions as well as secondary lung injury due to systemic insults such as trauma and sepsis. This medical air is often produced on site through devices which draw, compress and filter outside air in order to […]

Medical air is commonly used in healthcare institutions as a life support drug distributed to patients. This medical air is often produced on site through devices which draw, compress and filter outside air in order to redirect it into buildings. However, depending on the outdoor conditions, the state of the ventilation system or the presence […]

Neisseria meningitidis (Nme) is a bacterial pathogen that often colonizes the upper respiratory tract of humans without symptoms, but which may also develop into rapidly-progressing sepsis and meningitis that can be fatal. Nme has evolved elegant means to specifically interact with human cells and proteins in order to colonize, survive and the evade host immune […]

Lithium ion batteries (LIBs) are considered the top candidates among electrochemical energy storage systems (ESS) due to their high energy density which has triggered the growth market of popular devices such as cell phones, computers, electric vehicles (EV) etc. As ESS, LIBs are continuously charged and discharged during their utility. The charge/discharge cycle is known […]

In the last decade, lithium-ion batteries (LIB) have become the most popular power sources for consumer devices, telecommunication, energy storage systems, as well as electric vehicles. This type of batteries is indispensable in maintain our modern society. GBatteries have developed an active battery management system (ActiveBMS), which hinders LIB degradation mechanisms, such as the anode […]

With every surgery, there is always a risk that a post-operative complication could occur. NERv Technology Inc. is developing a disruptive solution to post-operative complications. NERv is developing an implantable biochip with multiple biosensors capable of detecting post-operative complications in real-time. NERv has developed a macro-prototype capable of detecting internal bleeding and the leakage of […]

Febrile syndromes are among the most common causes of global illness accounting for approximately two billion episodes annually. However, most infections are self-limited and only rarely do they progress to critical illness. Our current inability to rapidly identify the small proportion of individuals who will progress to life-threatening infections (LTIs) is a major barrier to […]

The global demand for engineered wood products (EWP) is increasing and in the last two decades, timber has captured substantial market shares from the mineral-based solid construction materials, particularly in the construction of residential and non-residential buildings. Although, the production of glue laminated timber (Glulam) and cross laminated timber (CLT) engineered wood products has been […]

The visualization/decision support work encompassed by this application addresses key elements of the upgrade path for that strategic part of IBM Canada’s smarter cities product and service portfolio– as urban transport systems evolve, their escalating complexity requires more advanced visualization tools and practices. The specific project proposed for development within the MITACS brief is:• development […]