Legal, regulatory and ethical framework for a health tech startup

More than 2 million Canadians require personal assistance at home because of age or disability, with at least 15% of them reporting having unmet needs. When needs go unmet, we know that people are unable to maintain employment because they cannot predict their schedule. We know that they experience significant stress and mental health challenges […]

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Development of new RNA-guided dual-cleaving nucleases

Gene editing with RNA-guided nucleases based on the CRISPR bacterial defence system (clustered regularly interspaced palindromic repeats) has revolutionized both basic science and therapeutic applications. However, CRISPR associated (Cas) nucleases are not optimized for all types of gene-editing applications. In particular, the double-strand breaks made in DNA by the Cas proteins are imperfectly repaired by […]

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Early Biomarkers for Prediction of Chemotherapy-induced RNA Disruption in Tumour Cells

Chemotherapy agents can induce the degradation of a molecule in tumour cells called RNA. We call this phenomenon “RNA disruption”. High tumour RNA disruption after about 1 month of chemotherapy predicts for complete tumour destruction and improved cancer patient survival. We and Rna Diagnostics, Inc. are using this knowledge to predict patient outcome from chemotherapy. […]

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Artificial Intelligence for Condition Assessment of Critical Infrastructure

Unexpected deterioration and failure of concrete infrastructure causes major disruptions and in the most severe cases, results in lives lost. According to the 2019 Canadian Infrastructure Report Card, Canadian public infrastructure is at risk therefore, detecting and addressing deterioration in such structures is crucial. The Damage Rating Index (DRI), a reliable novel quantitative microscopic procedure, […]

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The Pan-Canadian Immunoglobulin Database: Enabling Utilization Reporting and Personalized Treatment Using Data Mining Techniques for Immunoglobulin

Immunoglobulin (Ig) is a blood product that is used for people who either lack IgG antibodies or require immunomodulatory therapy for life-threatening autoimmune conditions. The use of Ig products continues to increase each year, at an average rate of 8%. The COVID-19 pandemic has introduced additional stress on the Ig supply due to a reduction […]

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Nuclear Decommissioning Management using Building Information Modeling and Augmented Reality

Integrating augmented reality (AR) technology with decommissioning workflows will open new avenues to remotely visualize and interact with Building Information Models (BIMs), enabling safe and cost-effective decommissioning processes of nuclear power plant (NPP) structures. Research is proposed here to advance new NPP decommissioning workflows through novel sensing, computing, and artificial intelligence (AI) methods within the […]

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Improving the Properties of Biopolymers through Chemical Functionalization; Adding Value to an Industrial Side Product for Cascades

This project, in partnership with Cascades, will develop novel functional materials prepared from a biopolymer generated at Cascades. The development of these novel materials and composites will help to fine-tune the properties of the final paper sheet produced at Cascades and access high performance materials for many of their core business activities. The new polymer […]

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Developing a Data Science Tool for Open Government Datasets

In an effort to build public trust, the Government of Canada has made a commitment to move toward an Open Government, where government data will be easily accessible and shared broadly. For the public to benefit from Open Government sources, they will need tools that will allow them to analyze and interpret the data accurately. […]

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