Assessment of indoor environmental quality in the school building

Indoor environmental quality in schools is one of the major issues that should be considered. Indoor air quality (freshness and cleanness of air inside the building) and thermal comfort (the comfortable condition when no one is feeling either too hot or too cold) in schools can have significant impact on children’s health, learning and productivity. […]

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Stability and antioxidant properties of pharmaceutical and nutraceutical products

Nutraceuticals are being used ubiquitously, but seldom undergo rigorous testing. This study is focused on two primary aspects of studying natural health products, specific cannabis and its oils. The first objective is to determine the shelf life (product stability) by performing a series of tests to accelerate the ageing process in order to provide an […]

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Characterizing the Mode of Action of Novel Boron-Containing Antifungal Agents for Crop Protection

Fungal pathogens of agriculturally significant crops pose a serious threat against global food security. This is exacerbated by the limited classes of fungicides that are commercially available for the farmers and the rapid emergence of resistance against the existing fungicides. Furthermore, resistance against agricultural fungicides can poses serious threat to human health as it can […]

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Defining and Targeting Autoimmune Liver Disease

The liver is the largest solid organ in the body and is critical for metabolic and immune functions, however huge gaps still exist in our basic knowledge of the human liver. Due to challenges in obtaining human liver tissue and the fragility of liver specimens, little is known about the cells that make up the […]

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Production of isomalto-oligosaccharides with tailored technological and nutritional functionalities

The project will assess functional benefits of an isomalto-oligosaccharide preparation. Isomalto-oligosaccharides are functional oligosaccharides that are applied as functional food ingredients to reduce the caloric content and the glycemic load, as a source of dietary fibre, and to support homeostasis of intestinal microbiota. Regulatory approval of the products and the functional claims requires scientific support […]

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Development of an antibacterial membrane for purification of floodwater

When floods happen, municipal water distribution systems are damaged and the residents will not have access to clean water. As a result, the will face the risk of health effects from water-born bacteria and pathogens increases. In this project, we proposed a system to purify the water stored frim flood water. This purified water can […]

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A mass balance modelling framework for chemicals and their primary metabolites for ecological and human health assessment – Year two

Chemicals manufactured and used in society degrade through physical and biological processes (e.g., photolysis, biotransformation) into break-down products (e.g., metabolites). Most “parent” chemicals can breakdown relatively quickly so that they are not persistent or bioaccumulative; however, some metabolites formed during the degradation processes can persist in the environment thus requiring consideration for ecological and human […]

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Development of a next-generation in vivo human gene-editing therapeutic platform – Year two

The over-arching goal of our project is to develop a robust next-generation gene-editing platform to repair the deleterious mutations that are responsible for genetic diseases such as Cystic Fibrosis and cancer. First-generation precision endonuclease technologies have been tremendous for in vitro gene disruption studies and ex vivo treatments, but there has been limited success at […]

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Modeling Dune Roughness in a Large Sand-bedded River – Year two

Dunes are common bed features in large sand-bedded rivers and are significant sources of in-channel roughness. Reliably estimating roughness is crucial for the prediction of flood flows, but roughness is crudely represented in hydraulic models widely used by environmental consultants and engineers. Roughness is treated as a calibration knob in these models, adjusted to force […]

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Constrained Batch Estimation for Train Positioning with Inertial Sensors

Similar to current efforts in the automotive industry, there is a substantial interest in developing fully autonomous trains. One of the key steps towards enabling autonomous operation is being able to accurately estimate train position and speed. In addition to this, better estimates will also increase safety and reduce distance between trains, allowing more frequent […]

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