Enhancing equine tendon repair: evaluating the synergistic effects of mesenchymal stromal cells and hyaluronic acid in a collagenase-induced injury model

This research project aims to enhance the treatment of common tendon injuries in horses, a prevalent issue causing economic losses in equine sports. Despite various treatments, there’s a crucial need for more effective solutions. The study focuses on comparing the impact of Mesenchymal Stromal Cells (MSCs) alone to a combination of MSCs and Hyaluronic Acid […]

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Agile digital twin solutions for enhanced utility-scale photovoltaic fleet energy performance

This research project enables internship personnel, guided by their industry sponsors, to develop advanced software features for designing and operating vast solar power farms. Creating a digital twin of the system, these computational models apply the latest solar technologies to efficiently harvest light from the whole environment (sun, sky, and ground) under the complex shading […]

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Assessing the Efficiency of Extracellular Vesicles for the Therapeutic Delivery of Modified mRNA

Extracellular vesicles (EVs) are tiny, membrane-based particles that cells release into various bodily fluids. They serve as messengers, facilitating communication between different cells in the body and, therefore, playing pivotal roles in modulating various biological processes. They achieve this by transporting a diversity of bioactive cargos, including RNA molecules. Over the past decade, our understanding […]

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Développement d’un revêtement barrière à base de complexes polyélectrolytes pour le papier

Les revêtements à base de complexes polyélectrolytes (CPE) sont de plus en plus reconnus pour leur capacité à protéger et à conférer différentes propriétés à de nombreux substrats tels que le textile, le bois et le papier. Composés d’un polyanion et d’un polycation qui se lient par interactions électrostatiques, ces systèmes offrent l’avantage de pouvoir […]

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Portable Colorectal Screening Colorimetric Metabolite Biosensor

This project involves designing a portable biosensor that measures the concentration of multiple metabolites in a person’s urine. The device measures the colour of the urine after reacting with the developed reactions to get metabolite concentrations. These concentrations are input to an algorithm to get a diagnosis. The first test will screen for colorectal cancer. […]

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Reinforcement Learning Approach for Improving the Dynamic Response of Frequency in Low-Inertia Islanded Active Grids

The structure of power grid is changing due to the integration of distributed energy resources, especially the renewables and energy storage. These resources with power electronic converters provide additional controllability to grid operators and provide the capability of operating the interconnected gird as several active decentralized systems for enhancing system reliability and maintaining system resiliency. […]

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Robustness of Reinforcement Learning to Attacks and Adversarial environments

Reinforcement learning algorithms are successfully employed in diverse industries, for instance in autonomous driving, trading or gaming. However, their generalization especially in critical-decision making systems has raised concerns about their robustness to attacks. The 22nd recommendation issued by the White House (2016) to prepare for the future of AI states: ”Agencies (…) should ensure that […]

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Triassic-Early Jurassic Central Atlantic and mid-Cretaceous Scotian Margin Geochemical, Organic, and Biostratigraphic Events – a test case for molecular sequence stratigraphy

Development of oil and natural gas production in Atlantic Canada has mainly occurred in the offshore of Newfoundland, Labrador, and Nova Scotia. Energy Nova Scotia has estimated reservoir potential for Nova Scotia has been as high as 120 trillion cubic feet of natural gas and 8 billion barrels of oil. These reserves occur along the […]

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Role of Ribosomal Protein Ubiquitination in Chemotherapy- and Stress-induced RNA disruption in Tumour Cells

We have observed that chemotherapy agents can induce RNA degradation in tumour cells, a phenomenon called “RNA disruption”. Interestingly, we also found that high tumour RNA disruption after 2-3 cycles of chemotherapy predicts for complete tumour destruction after treatment and improved cancer patient survival. We and Rna Diagnostics, Inc. are using this knowledge to identify […]

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Multi-material Additive Manufacturing of Functional Ceramics

This proposal involves using 3-D printing technology to form a ceramic sensor. The sensor can be used by navies to detect submarines. The ceramic sensors are either an underwater sound projector, an underwater microphone, or both. The 3-D printing technology should allow larger, more sophisticated sensors to be manufactured. The technology should simplify the build […]

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Bioenergy production through mixed culture

The adverse impacts of fossil fuels on the environment, specifically climate change, have intensified the need for finding a sustainable alternative source of energy. Numerous studies have postulated that biotechnology development, focusing on biofuel production processes, could be a suitable solution for sustainable energy production. The utilization of microorganisms, such as microalgae, is one of […]

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Wild Atlantic Salmon Watersheds

The rate and magnitude of environmental change present a threat to freshwater fish populations. In Atlantic Canada the impacts to the freshwater ecosystems will arise through elevated water temperatures, alterations in precipitation, variability in ice cover and frequency of natural and man-made disturbances. In addition, temporal and spatial changes to precipitation alter seasonal flow patterns […]

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