Optimization and Scale-Up of a Biomanufacturing Process for Anellovirus-Based Vectors for Gene Therapy Applications

Gene therapy is a cutting-edge treatment that can fix or replace faulty genes to treat diseases, but producing the necessary gene delivery cargo, called vectors, is currently expensive and complex. Many of today’s vectors also trigger immune responses in patients, limiting their efficacy. This project explores a new type of vector made from a harmless […]

Read More
Scalability Development of Fc3TSR Preparation Using Shake Flasks and Bioreactors

This project will help improve the way a promising new cancer treatment protein, called Fc3TSR, is made in the lab. Fc3TSR has shown the ability to shrink tumors by changing how blood vessels grow in cancer, making treatments like chemotherapy more effective. However, making enough of this protein for further testing and future use is […]

Read More
Platform Governance and Gendered Misinformation

The Centre for International Governance Innovation (CIGI) is a leading think tank focused on developing policy solutions to address the governance challenges of emerging digital technologies. My proposed research directly supports CIGI’s core areas of digital governance, platform regulation, and misinformation policy by analyzing how extremist and gendered misinformation adapts within the affordances of digital […]

Read More
Realtime AI Scenario Platform

In recent years, the advancement of Artificial Intelligence has revolutionized technology and the way we use and interact with things online. The technology promises to transform how we interact with services, communicate with people, and find data most useful to us. The project focuses on software development to further develop an existing software involved in […]

Read More
Supporting Savouring and Positive Affect at Work with Personalized AI-Generated Images for Improving Mental Well-being

Workplace wellness programs often fail to improve mental health due to minimal uptake and engagement. Digital tools for mental health support are becoming increasingly popular; however, work programs are typically delivered through in-person formats and focus on more severe forms of support (e.g., offering leaves of absence) which often results in low engagement from the […]

Read More
Machine Learning-Based Air Gap Prediction for Safe Vessel Passage Under Bridge

The Halifax MacKay Bridge is a critical passage for maritime traffic, requiring accurate air gap predictions to ensure safe vessel clearance. This project will develop a machine learning-based forecasting model that estimates air gap values at 30-minute, 90-minute, and 72–96-hour intervals. Using data from the Port of Halifax, including tide levels, weather conditions, and traffic […]

Read More
Population Viability Analysis of Blanding’s Turtles in Nova Scotia

Freshwater turtles are one of the most at-risk vertebrate groups, with nearly two-thirds of species facing extinction risk. Nest predation by mammals is a major threat to freshwater turtles, which has resulted in community-based nest protection efforts in many regions around the world, including Nova Scotia, Canada. Although widely implemented, the efficacy of nest protection […]

Read More
Linking Pleistocene glacial processes and modern groundwater dynamics: a case study of the sediment–bedrock interface in Guelph, Ontario

Groundwater is the main source of drinking water for the City of Guelph, but understanding how it flows underground is complicated by the region’s glacial history. During the Pleistocene, glaciers repeatedly moved across southern Ontario, shaping the land and overlaying sediments onto the underlying bedrock. The resulting sediment?bedrock interface is vital because it influences how […]

Read More
Assessing Soft Skills in Higher Education: Best Practices and Tools for Holistic Admissions

Soft skills like communication, self-awareness, resilience, or empathy are important for individuals to succeed in higher education (e.g., medical, engineering, or business school). It is therefore important to effectively assess such soft skills when admitting students into education programs. Yet, such assessments must demonstrate predictive validity (i.e., performance in a test or interview should be […]

Read More
Innovations in Mass Cytometry

Biological systems are exceptionally complex. To understand the biochemical processes that influence diseases in whole organisms, information about all the cell types present and their activities is required. Mass cytometry is a Canadian invention that enables the simultaneous quantification of a large number of parameters at the cellular level in heterogeneous biological samples. Mass cytometers […]

Read More