Development of Advanced Machine Learning and Artificial Intelligence Models in an Open Cloud-Based Platform to Accelerate Drug Discovery (AIRCHECK)

The Artificial Intelligence Ready CHEmiCal Knowledgebase (AIRCHECK) is an open platform developed to share and analyze large-scale, freely accessible chemical activity data. AIRCHECK is specifically designed to integrate high-throughput chemical screens data generated from DNA-encoded libraries (DEL) and Affinity Selection Mass-Spectrometry (ASMS). AIRCHECK aims to become a global platform that advances Machine Learning (ML) and […]

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Collaborer pour une gestion circulaire et durable des eaux usées

Divers types organisations doivent de plus en plus travailler ensemble pour résoudre des problèmes mondiaux et locaux. Cependant, des divergences d’opinions et de secteur d’activité peuvent rendre cette collaboration difficile. Ce projet de recherche, en partenariat avec La Serre+, a pour objectif de comprendre, par une analyse historique de la démarche, comment différents groupes peuvent […]

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Outil d’aide à la décision pour réduire les émissions de gaz des installations de production d’œufs du Québec

Pour répondre aux nouvelles exigences des consommateurs, l’industrie ovocole vise à modifier la façon de produire en transitant des systèmes de cages traditionnelles vers des systèmes de logement alternatifs, tels que les cages enrichies et les volières. Ce changement, bien qu’avantageux pour le bien-être animal, complique la gestion de la qualité de l’air en raison […]

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Cold-season subtropical air mass intrusions into the Saint-Lawrence River Valley: dynamic-thermodynamic impacts on extreme precipitation and regional climate change

The heavily populated region of Québec’s Saint Lawrence River Valley (SLRV) experiences among the largest number of hours of freezing rain on the North American continent. Some of the region’s most impactful freezing rain events, including the Great Ice Storm of 1998 and the recent April 2023 ice storm, were characterized by very warm, moist […]

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3D Interactive Immersive Experience in Hospital and Long-Term Care

This study proposes to address these gaps using 3D Interactive Immersive Experience technology. By leveraging advanced 3D projection and sensor systems, the project will create accessible, engaging, and interactive virtual environments without reliance on headsets. Research will be conducted with older adults living with dementia in both a hospital unit and a Canadian LTC facility, […]

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High-resolution UAV-LiDAR Mapping for Assessing Erosion and Infrastructure Vulnerability Along the Niagara Escarpment

This project explores the critical geohazards affecting the Niagara Escarpment using advanced UAV-LiDAR technology. By mapping erosion patterns and assessing infrastructure vulnerabilities at sites like Shorthills, Wainfleet, and Balls Falls, the research aims to enhance public safety and inform conservation strategies. A key outreach component, “GeoHikes”, will engage the public through interactive 3D models and […]

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Redefining Cancer Risk Assessment Using Duplex Sequencing

The current gold standard to assess cancer risk of chemicals and other consumer products is the 2-year rodent cancer bioassay, which is time-consuming, expensive, and does a poor job at predicting the potential for cancer in humans. DupSeq is a cutting-edge, ultra-precise genetic analysis tool that can identify subtle changes in DNA, providing more comprehensive […]

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Analyses du potentiel d’utilisation des autres mesures de conservation efficaces par zone (AMCE) pour la connectivité d’un réseau écologique dans le sud du Québec

La perte d’habitats mène à la fragmentation du paysage, ce qui engendre des changements dans la structure et le fonctionnement des écosystèmes résiduels tout en provoquant également des pertes de biodiversité, de fonctions et de services écologiques. Ce phénomène risque de s’accentuer dans les prochaines décennies en raison des changements globaux et de l’accroissement de […]

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A Wearable Electrical Vestibular Stimulation System for Tracking and Enhancing Human Balance and Gait

The vestibular balance system detects linear and angular head motion and plays a role in stabilization of human balance and walking. Age-related vestibular disruptions increase fall risks for a large fraction of our elderly populations and make it increasingly difficult to continue living activity and independently, both of which have very large associated healthcare costs. […]

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Improving the efficacy of lung delivery of gene editors through optimized lipid nanoparticle formulations to repair cystic fibrosis-associated mutations in human lungs

Cystic fibrosis (CF) is one the most common life-shortening inherited diseases. In the past, patients rarely survived into adulthood; and currently, even with treatment, patients still often require difficult lung transplants. New drugs called protein modulators are a game-changer for CF patients; however, they require twice daily lifelong administration and cannot offset the pre-existing lung […]

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