Immunotherapeutic targeting of CD133 in adult brain tumors and understanding tumor microenvironment in Glioblastoma

Glioblastoma (GBM) is an aggressive adult brain tumor, and in spite of standard of care (SOC) with radiation therapy and chemotherapy with temozolomide tumor re-growth (or recurrence) and patient relapse are inevitable. There is compelling evidence that suggests SOC can debulk the tumor but cells endowed with treatment-resistant properties (e.g. expressing the protein marker CD133) […]

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Assistance tools to build taxonomy of skills and to search for experts

In many applications, we need to find the right person with the required expertise (skills) for some task. To enable this, it is necessary to extract and organize the skills of different persons in a taxonomy. This project aims at developing a taxonomy of skills for the National Bank of Canada. Currently, a small taxonomy […]

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Effect of Saccharomyces boulardii CNCM I-745 in the prevention gluten immunopathology.

The only treatment for celiac disease (CeD) is a strict gluten-free diet, which is very difficult to follow. Despite following gluten-free diet, many celiacs experience ongoing inflammation and symptoms, highlighting the need for additional therapies. We have shown that celiacs have an altered composition of bacteria in their gut, and this leads to defective bacterial […]

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Novel Boundary Element Method for Inductance Extraction in Cables of Complex Cross-Sections

The proposed project is dedicated to fast resistance and inductance extraction for multiconductor transmission lines. Since the complexity of power cable designs has grown significantly over the past decade, fast and accurate tools for electromagnetic characterization are required. The cable models presently used by Manitoba Hydro however are overly simplified compared to the ones available […]

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Wireless gas sensor based on activated carbon and nanofibrillated cellulose for detection of food spoilage

Monitoring the quality of perishable food is critical for reducing the societal costs. A wireless intelligent gas sensor based on biomass/heavy oil-derived activated carbon will be prepared to monitoring the spoilage of food. Agricultural/forest biomass residual materials such as straw, sawmill waste, and logging residue, and cheap and abundant bitumen are feedstocks yielding high porous […]

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Macrofungal biodiversity in coastal temperate rainforests of British Columbia

Coastal temperate rainforests hold a high biodiversity of living organisms, including many fungal species. The diversity of fungi remain poorly described in forests of BC. In the proposed study, we will document these species and improve our understanding of ecosystem complexity by gathering essential baseline information on fungal communities. This will be useful for applied […]

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Développement d’un prototype de modèle à base d’agents pour comprendre la construction de la mémoire collective au sein d’une communauté

Cette recherche vise à développer un outil prototype qui nous permettra de reconstruire les mémoires collectives des peuples indigènes et de comprendre leur approche vis-à-vis de la gestion des enjeux d’adaptation aux changements climatiques auxquels ils sont confrontés. La plupart des peuples indigènes cultivent la fidélité aux plus profondes mémoires qui à la fois relient […]

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Business Analyst (BA) Impact on Business Agility and Data Analytics

Digital Transformation of business, combined with globalization through outsourcing, has create an increasingly fast-paced, competitive environment for most businesses. Additionally, new disruptive technologies such as Artificial Intelligence and Blockchain are just beginning to open new opportunities for the next wave of Digital Transformation. Agile concepts have accepted in information systems (IS) development for more than […]

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Synthesis of Three Minor Cannabinoids

The recent legalization of marijuana across the globe has sparked new interest in studying the health benefits of non-psychotropic cannabinoids. The majority of the studies have revolved around cannabidiol as it can readily be isolated in high quantities from hemp. Preliminary medicinal studies into CBD have revealed its promise as a treatment for anxiety, and […]

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