A novel home cage testing environment for frontal cortical neuronal recording in marmosets

Marmosets are primates with a brain that has comparable anatomical-functional subdivisions to those of higher primates, including humans. It is thus a valuable model for investigating the neural bases of behaviour and cognition and there has been a substantial increase in marmoset use in translational neuroscience research over the last few years. A comfortable environment is critical for marmoset neurophysiological testing. Rogue Research is developing a unique apparatus that attaches to the monkeys’ homecage and will permit automated neurophysiological testing using a number of devices, such as a touchscreen for stimulus presentation, reward systems, eye-monitoring, and physiological setups for recording brain activity during research tasks. In developing and testing the system, we shall also address a major scientific question. Humans and macaque monkeys have the capacity to hold and manipulate in working memory the precise order of a short series of visual stimuli seen only once. TO BE CONT’D

Faculty Supervisor:

Michael Petrides

Student:

Partner:

Rogue Research Inc

Discipline:

Life Sciences

Sector:

Manufacturing; Professional, scientific and technical services

University:

McGill University

Program:

Elevate

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