Analysis of a Genetic Mutation in a Gene for Association to Coronary Artery Disease

Coronary artery disease (CAD) occurs when buildup of plaque causes blockage of oxygen to reach the heart. When a total blockage occurs, this leads to heart attacks. CAD is the leading cause of death worldwide and this research will be conducted on a mutation found in a gene associated with plaque build up and analysis will be undertaken to determine the relationship between this mutation and the susceptibility of attaining the disease. Our expected results will allow us to understand what effect this mutation has on a gene related to CAD and will add to our current understanding of genetics in the development of CAD.

Faculty Supervisor:

Tony Harris

Student:

Partner:

National University of Singapore

Discipline:

Life Sciences

Sector:

Education

University:

University of Toronto

Program:

Globalink Research Award

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