Analysis of protein interaction complexes by advanced mass spectrometry workflows – Year Two

By studying protein complexes, scientists gain insight into how cells are regulated and how aberrations in protein-protein interactions cause disease. Mass spectrometry is a technology that allows proteins to be identified and quantified in a systematic and unbiased manner. New technologies from mass spectrometer vendor SCIEX aim to improve the throughput, accuracy and reproducibility of the analysis of protein complexes. Successful completion of this project will provide SCIEX with validated data on the utility of these technologies to applications of considerable interest to scientists in the proteomics field. This feedback will be incorporated with other data from internal or external sources to help SCIEX make an informed decision on how best to market these technology improvements and to also guide potential new redesigns of mass spectrometry hardware.

Faculty Supervisor:

Ann-Claude Gingras

Student:

Partner:

University of Toronto;SCIEX;Sinai Health System

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Biotechnology; Technology

University:

University of Toronto

Program: