Associations between sleep disturbances and cognitive performance in Parkinson’s disease: a multimodal neuroimaging study

This project aims to explore the association between sleep disturbances and cognitive function in Parkinson’s disease (PD) through multimodal neuroimaging. Sleep issues, including insomnia, excessive daytime sleepiness, and rapid eye movement sleep behavior disorder, affect a significant portion of PD patients and are linked to cognitive impairments. This project will investigate how these sleep disturbances interact with cognitive deficits and the underlying brain regions, using advanced imaging techniques to understand the relationship between disrupted brain connectivity, dopamine deficits, and cognitive decline. The findings will enhance our understanding of the neural mechanisms involved, in order to help improve the quality of life and care for PD patients. This research is expected to benefit the participating institutions by contributing valuable insights into PD’s complex neurobiological processes and, eventually, offering potential targets for therapeutic interventions.

Faculty Supervisor:

Oury Monchi

Student:

Partner:

Umeå University

Discipline:

Life Sciences

Sector:

Education

University:

Université de Montréal

Program: