Blood pressure and vascular biomechanics: insights from numerical simulation models

High blood pressure leads to stroke, heart attacks and heart failure. Despite a century of research, the target
blood pressure is still a matter of debate. This limitation is likely related to the oversimplification of the functioning
of the cardiovascular system. Using novel biomarkers of blood pressure and mechanical properties of the arterial
system, we believe that it will be possible to move towards a more personalized goals in the treatment of high
blood pressure. To do so, we need to develop a better understanding of the cardiovascular physiology through
numerical simulations, which are now possible. The candidate will develop novel tools to develop a better
understanding of the blood vessels properties and will use this knowledge in conjunction with the simulation
models to examine the impact of changes in arterial properties along the arterial tree and their impact on the
arterial flow pattern. This innovative approach is in line the institutions mission to improve health through
innovation.

Faculty Supervisor:

Mohsen Agharazii

Student:

Partner:

Fondation du CHU de Québec;CHU de Québec-Université Laval

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology

University:

Université Laval

Program: