Delayed-sustained drug release from electrostatic dry coated capsules with ultra-fine powders

Pharmaceutical drugs can be made in different forms such as tablets, solutions, capsules, etc. depending on ease of administration, the effect of the drug on the body, and the effect of the body on the drug. Capsules are composed of an outer gelatin shell in which the drug is packed. They are more expensive to produce compared to tablets, but can include drugs in liquid forms, drugs with low compressibility, or slowly dissolving drugs. To protect the drug from contamination, the capsules need to be coated. The present way to coat a capsule is through an aqueous process which is long and expensive. Instead, Zhejiang University of Technology is working on developing a new technique to coat capsules using electrostatic dry powder. The aim is for the capsules to delay the release of the drug until it is in a specific site such as the intestine. TO BE CONT’D

Faculty Supervisor:

Charles Jia

Student:

Partner:

Zhejiang University of Technology

Discipline:

Engineering

Sector:

Education

University:

University of Toronto

Program: