Developing a nanoparticle platform for cell-free protein engineering

This project aims at developing a nanoparticle-based technology that will allow us to engineer and screen proteins for catalytic activity in a cell-free environment. The proposed method will be faster and robust compared to conventional protein engineering techniques. This will be achieved by combining cell-free protein systems (CFPS) and magnetic nanoparticle (MNP) to make screening of protein activity easier. Finally, we aim to develop a method that can be adapted for various protein activities. Galenvs aims at commercialising this technique and make it readily available for various applications. The research exchange will result in a PhD thesis project and impart essential skills required in biotechnology industry. The intern will receive training in an industry setting and will learn k y techniques such as MNP synthesis and characterisation, CFPS, development of assays, and next-gen sequencing.

Faculty Supervisor:

David Kwan

Student:

Partner:

Galenvs

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

Concordia University

Program: