Development and Validation of Optimized Bioprinted 3 D Psoriatic Skin Models

Psoriasis is an inflammatory chronic skin disease for which we skin models to study.
Dr. Roxane Pouliot (academic supervisor) group at University Laval (Quebec) has previously developed a human psoriatic skin model using skin cells to which lymphocytes (from human blood) have been added. The goal of this project is to further optimize the skin model in collaboration with Axolotl Biosciences (the industry laboratory partner, British Columbia).
We will use cells from skin and blood to build a skin model of psoriasis using the technique of bio printing at the industrial partner (Axolotl Biosciences) lab. Axolotl Biosciences envisions delivering innovative products that enable the 3D bioprinting of humanized tissue models for advancing medicine. The challenges Axolotl Biosciences aims to solve through this project is to apply their techniques and expertise to contribute to the optimization/improvement of the human skin model developed at the laboratory of Dr. Roxane Pouliot.
This would allow us to develop a new model and validate it to study Psoriasis. This optimization will lead to a new generation of psoriatic skin models to study the disease pathogenesis, prognosis, and test potential therapeutic options. Results will be published and presented/publicized during scientific events.

Faculty Supervisor:

Roxane Pouliot

Student:

Partner:

Axolotl Biosciences;Stem Cell Network

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

Université Laval

Program: