Development of mass spectral methods for the detection sulfide modification sites in proteins.

Proteins are large molecules found in all tissues they are composed of amino acids. Proteins perform most of the function in our bodies. Diseases are the result of changes to specific amino acids in proteins that result in alteration or complete loss of protein function. Pharmaceutical interventions in controlling or eliminating diseases depend on the identification the altered amino acid residues. The proposed project is designed to develop new mass spectrometry based methods for the identification of the amino acid residues in proteins that are susceptible to modification/alteration. The techniques being developed will be of interest to biothechnology, pharma and medical device industries both in Canada and in Turkey.

Faculty Supervisor:

Bulent Mutus

Student:

Partner:

Akdeniz University

Discipline:

Physics

Sector:

Education

University:

University of Windsor

Program: