Establishing the reliability of DTI and resting-state fMRI as markers of traumatic brain injury Year Two

The proposed research will investigate two brain imaging measures that hold potential as tools for the diagnosis and assessment of traumatic brain injury (TBI), including mild TBI (mTBI)/concussion. One type of image provides information about structural damage to the brain’s anatomical connections, and the other about the functional connectivity of networks of brain regions that underlie many mental abilities. The proposed research will investigate the relationship between these measures, their reliability an individual over time, and also the comparability of each measure between different scanners and software applications. The project will provide fundamental knowledge essential to the future development of accurate, objective, and individualized tools to diagnose and characterize mTBI, to track its progression over time, and to guide treatment and return-to-work/play decisions

Faculty Supervisor:

Michael Noseworthy

Student:

Partner:

Synaptive Medical Inc

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Manufacturing; Professional, scientific and technical services

University:

McMaster University

Program: