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Multiple myeloma (MM) is the second most common hematological cancer in Canada, affecting
an estimated 2,300 people in 2011. Farm work is most consistently associated with an increased
risk of MM. Occupational exposure to pesticides has been linked to increased MM risk in
Canadian and European studies. Previous investigations mostly focused on individual pesticide
exposures, however, the effects of the use of multiple pesticides and different combinations of
specific pesticides have not been explored. The objective of this analysis is to examine the impact
of the use of multiple pesticides on MM risk. In addition to evaluating specific pesticide
combinations, an analysis will be carried out to examine the association between the total number
of pesticides used and MM risk. Multiple pesticide exposures more accurately capture how
pesticides are used in agriculture, therefore this analysis will contribute to our understanding of
the role that agricultural exposures and other factors play in the development of MM. Examining
common pesticide combinations and identifying……
Susan Bondy
Cancer Care (Ontario)
Life Sciences
Health and Related Sciences & Technology
University of Toronto
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