Hemodynamic correction for widefield optical imaging of fluorescent calcium indicators

Imaging brain activity patterns across different brain regions is important for understanding both how the brain works, and how it malfunctions in disease. Recently, development of new optical imaging techniques have allowed imaging such patterns during behaviours and in models of disease. However, one problem with these imaging techniques is that blood adsorbs light, which complicates the interpretation on the origin of these signals. Here we aim to test and develop different approaches to improve the accuracy on interpreting the origin of these brain imaging signals. This will lead to a better understanding of brain processing in health and disease.

Faculty Supervisor:

Ravi Rungta

Student:

Partner:

LabeoTech

Discipline:

Life Sciences

Sector:

Manufacturing

University:

Université de Montréal

Program: