Impact of intracellular mechanics on electro-mechanical coupling in heart failure with preserved ejection fraction in humans

The proposed project aims to study how a novel microRNA can improve heart muscle function in patients with heart failure. This microRNA helps heart muscle cells relax better, which is a key issue in patients with heart failure with preserved ejection fraction (HFpEF).
By combining the biophysics expertise and force measurements techniques developed at McGill University and the advanced electrophysiology techniques available at the University of Montpellier, this research will deepen our understanding of how heart cells work. This research will bridge two different but complementary disciplines to fill a crucial gap in our understanding of the heart. The knowledge exchange between these two institutions will help us find new ways to treat heart disease, benefiting both research teams and the broader scientific community.

Faculty Supervisor:

Allen Ehrlicher

Student:

Partner:

Université de Montpellier

Discipline:

Life Sciences

Sector:

Education

University:

McGill University

Program: