Improving the delivery and efficacy of in vivo gene editing

Genetic diseases are a significant health and economic burden worldwide. Treatments for the majority of these diseases remain limited or nonexistent. One treatment approach is directly editing the DNA mutations that cause the diseases. However, getting DNA editors into specific areas and cells in the body can be quite difficult. This project looks at using lipid nanoparticles to deliver DNA editors to different places in the body to facilitate gene editing. The partner organization has expertise in lipid nanoparticle formulation and will benefit from a gene editing focus of this project to expand the range of therapeutics they are working on developing.

Faculty Supervisor:

Colin Ross

Student:

Partner:

NanoVation Therapeutics Inc.

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

The University of British Columbia

Program: