In vivo evaluation of smart nanocarriers for cancer therapy

Cancer is the leading cause of death worldwide. Despite of development of arsenal of medications to treat cancer, the efficiency of marketed medications has been drastically compromised by their unwanted and uncomfortable side effects. To address this problem, we have developed new nano-sized drug transportation carriers to deliver the drugs to the tumor tissue and break down and release them only once they are inside the environment of a tumor or cancer cell. This method cannot only prevent damage to the healthy tissues and organs in the body but can also protect drug against various physiological barriers in the body. Investigation of these drug nanocarriers in animal models is an integral stage for their entry into clinical application. Our research supported by Mitacs is aimed to investigate the therapeutic potentials of these nanocarriers by examining them in mice. TO BE CONT’D

Faculty Supervisor:

John Oh

Student:

Partner:

Peking Union Medical College

Discipline:

Life Sciences

Sector:

University:

Concordia University

Program:

Globalink Research Award