Integrating comparative genomics and Tn-Seq data to uncover genetic interaction networks in pathogenic bacteria

Antibiotic resistance is a rising threat worldwide, making infections increasingly hard to treat. This project aims to tackle this urgent issue by mapping out the hidden genetic relationships within harmful bacteria, including Escherichia coli and related pathogens. By analyzing vast amounts of genetic data, we will identify critical points—called genetic hubs—essential for bacterial survival. Targeting these genetic hubs could lead to the development of powerful new antibiotics, providing fresh solutions to protect public health and combat resistant infections effectively.

Faculty Supervisor:

Pierre-Étienne Jacques

Student:

Partner:

University of Manchester

Discipline:

Life Sciences

Sector:

Education

University:

Université de Sherbrooke

Program:

Globalink Research Award

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