Investigation of impact of predatory bacteria in simulated gut microbiome, Robogut

Gut microbiome stability appears to be essential for keeping health nowadays. Then, the needs to develop proper tools to modulate microbiome become important issue. In this proposal, we suggest predatory bacteria as microbiome modulator. Predatory bacteria are ubiquitous in the environment and non-toxic to mammalian cells. Recent researches proved the existence of predatory bacteria inside 92 humans’ gut and found relatioship between disease and their existence. Also, one groups added predatory bacteria into gut of rats for 7 days, beneficial microbes are increased. However, this researches are in early stage and we need to find good model to analyze impact of predatory bacteria inside gut microbiome by controlling many of factors.
Robogut, chemostat with simulated gut microbiome, is perfect model to simulate impact of predatory bacteria inside gut microbiome without animal model. TO BE CONT’D

Faculty Supervisor:

Emma Allen-Vercoe

Student:

Partner:

Ulsan National Institute of Science and Technology (UNIST)

Discipline:

Life Sciences

Sector:

Life Sciences (not health); Health and Related Sciences & Technology; Biotechnology

University:

University of Guelph

Program: