L2M Validation / QC Automne 2025 / Next-Generation Paper Diagnostics: Point-of-Care Smart Detection of Infection

This project focuses on creating a low-cost, paper-based sensor that can quickly detect and archive Pseudomonas aeruginosa, a harmful bacterium found in both medical and environmental settings. This includes infections in hospitals and contamination in water systems—two areas where fast, accurate detection is essential for protecting public health. The sensor leverages smart electrochemical technology to specifically detect a signature molecule produced by the target bacteria, enabling rapid and accessible testing without the need for complex laboratory equipment or specialized training. In addition to real-time detection, the paper-based format allows the device to physically retain the sample, providing an integrated means of archiving for potential confirmatory testing or future analysis.

Beyond medical and water testing, the sensor also shows promise for use in biosecurity. With minimal adjustments, it could be adapted to detect other hazardous biological agents, making it valuable for emergency response, border screening, and public safety applications. Made of paper, the device is lightweight, inexpensive, and easy to dispose of safely through simple incineration, an important feature when handling biohazardous waste in remote or resource-limited settings. This makes it especially suitable for deployment in northern Quebec and Indigenous communities, where laboratory access and waste management options are often limited.

During this project, feedback from potential users and stakeholders (healthcare professionals, NGOs, and public health officials) will be gathered through structured interviews and fieldwork. This input will be used to validate the sensor’s design, usability, and relevance in real-world scenarios such as infection control, water quality monitoring, and crisis response. Insights will inform key aspects of commercialization, including pricing strategy, distribution models, and potential partnerships. These efforts will help the start-up refine its product and accelerate the development of a user-informed, field-ready diagnostic tool.

Faculty Supervisor:

Raphael Trouillon

Student:

Partner:

V1 Studio

Discipline:

Engineering

Sector:

Biotechnology; Health and Related Sciences & Technology; Clean Technology

University:

Polytechnique Montréal

Program: