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Modeling Human Cell Phosphorylation Network
It is believed that defects in the human cell phosphorylation network are related to at least 400 different diseases such as Cancer, Alzheimer, and Diabetes. The goal of this research is to model the components of the cell phosphorylation network (e.g. kinases, substrates, phosphatases, and SH2-PTB domain proteins) and their interactions, and ultimately to build a generic network model based on the cell samples from healthy individuals. This generic network model can be then compared to networks based on cell samples from various patients and used to design patient-specific drugs.
Faculty Supervisor:
Jan Manuch
Student:
Partner:
Discipline:
Computer science
Sector:
Professional, scientific and technical services
University:
Simon Fraser University
Program:
Accelerate
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