Novel product and prototype development for soft tissue regeneration

Laetech is developing novel technology for the treatment and reconstruction of soft tissue. Specifically, Laetech is harnessing the regenerative capacity of cells found in a patients own fat tissue. Due to the abundance of fat and relative confidence of harvesting it, fat derived cells have become a large area of interest for researchers and commercialization efforts. Laetech’s technology is enabling surgeons to add cells from a patient’s fat tissue to biomaterials to improve patient outcomes. We are currently exploring two main different products: 1. A functional biodegradable material that is to be used in conjunction with harvested and processed fat tissue (Adipograft). 2. The second product is a similar material formulation as the first product described but in the form of a thicker and more porous hydrogel material for the application as an alternative to fat grafting. The intern will be working towards the completion of three main objectives: Objective 1. To scale the material manufacturing to meet the requirements for a large animal model study. Objective 2. To develop a crosslinking strategy and methodology for the gingival tissue material product, while making regulatory considerations. Objective 3. To develop a functionalized version of Laetech’s material using antibody conjugation methodology or other methods that allow for a specific cell type (endothelial cells) to adhere to the material.

Faculty Supervisor:

Norah McRae

Student:

Partner:

Laetech

Discipline:

Engineering

Sector:

Manufacturing; Professional, scientific and technical services

University:

University of Waterloo

Program: