Optimization of injectable dense collagen gels in vitro and in vivo for bone tissue engineering

Bone defects may arise from trauma, congenital disease, tissue/vascular necrosis or tumor radiotherapy/excision. Rising rates of the ageing population are expected to dramatically increase the demand for orthopaedic procedures and associated waiting periods for patient treatment. Current techniques to repair and regenerate of mineralized tissues possess inherent limitation and may be overcome by tissue engineering. In this Globalink Research Award Proposal we will use an innovative technique for bone repair that will impact orthopaedic and dental (craniofacial) applications. By using a unique combination of tools already used in the clinic, we have developed a novel system for the production of highly defined injectable dense collagen-based gels for the delivery of bioactive glasses and cells in bone tissue engineering applications. TO BE CONT’D

Faculty Supervisor:

Showan Nazhat

Student:

Partner:

Université Paris Descartes

Discipline:

Engineering

Sector:

Education

University:

McGill University

Program: