Optogenetic feedback control to control gene expression using image processing techniques

Biomanufacturing is essential to growing Canada’s economy – as it provides a means to produce valuable and essential drugs, therapeutics, vaccines, and chemicals such that they are affordable and available for the Canadians who need them. In these facilities, biomanufacturing using yeast cells are becoming an attractive method for producing the valuable products because they can be rapidly produced and can result in larger quantities. In our Project, we will develop a miniaturized system that will search for genes that will tune the metabolic pathway toward efficient and large production of drugs of interest. Our complete system will use light to control these genes, and find which genes are critical to produce large quantities of a drug. When successful, we will have a new method for biomanufacturing optimization that can be applied to numerous drug production as well as new software workflow that can be integrated with Object Research Systems’ line of software products.

Faculty Supervisor:

Steve Shih

Student:

Partner:

Object Research Systems;Comet Technologies Canada Inc.

Discipline:

Engineering

Sector:

Information and cultural industries; Professional, scientific and technical services

University:

Concordia University

Program: