Probiotic modulation of mast cells

Probiotics are bacteria that provide health benefits when eaten. However it is difficult to identify which bacteria may have beneficial properties and therefore identification of new probiotics is a time consuming and expensive process. In this project the intern will examine the effect of different potential probiotic bacteria on a specific cell type, the mast cell, which plays an important role in food allergy. The project will determine if screening for the ability of bacteria to prevent mast cell activation will identify probiotics that could reduce allergic responses. The project will also identify how certain bacteria interact with mast cells, knowledge that would allow for the development of more effective probiotics. The successful completion of this project will provide Lallemand Health Solutions with a way to accelerate identification and development of new probiotics and identify new potential health benefits of existing probiotics.

Faculty Supervisor:

Paul Forsythe

Student:

Partner:

Lallemand Bio Ingredients

Discipline:

Life Sciences

Sector:

Agriculture; Manufacturing; Professional, scientific and technical services

University:

McMaster University

Program: