rTMS for post-covid-19 condition: A sham-controlled case series involving iTBS-300 and iTBS-600

The objective of the “rTMS for post-covid-19 condition: A sham-controlled case series involving iTBS-300 and iTBS-600” project is to determine the efficacy, feasibility, and tolerability of several iTBS variants (iTBS-300, iTBS-600) and sham stimulation in PCC patients. Secondarily, the aim is to examine signs of improvement in cognitive, affective, and functional symptoms following each iTBS variant.

This project is going to be an extension of an existing case serias which included 4 participants. The objective is to extend the number of participants to 30. The purpose of this study is to further examine the potential of non-invasive brain stimulation for improving symptoms of PCC. It is hypothesized that rTMS will be well-tolerated and safe in this population, and that positive trends in cognitive, psychiatric, functional and quality of life domains will be evident following excitatory stimulation of the prefrontal cortex. The primary outcome will be data on the efficacy of rTMS for improving post-COVID-19 conditions, as well as the extent to which it is tolerable and feasible for use with the PCC population.

Faculty Supervisor:

Peter Hall

Student:

Partner:

Bogomolets National Medical University

Discipline:

Life Sciences

Sector:

Education

University:

University of Waterloo

Program:

Globalink Research Award

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