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Targeting bacteriophage delivery of reprogramming transcription factor gene(s) to astrocytes in CNS by Intelligent Phagemid-Assembled Gene Expression (iPhAGE) technology
This project aims to develop a method for delivering reprogramming transcription factor genes to astrocytes in the central nervous system using Intelligent Phagemid-Assembled Gene Expression (iPhAGE) technology. By constructing specific gene blocks and fusion helper plasmids, synthesizing iPhAGE DNA, and purifying iPhAGE preparations, the project seeks to enhance transfection efficiency and assess immune responses and protection. The participating institutions will benefit from the advancement of biotechnological techniques and potential therapeutic applications for neurological disorders.
Faculty Supervisor:
Roderick Slavcev
Student:
Partner:
National University of Food Technologies
Discipline:
Life Sciences
Sector:
Biotechnology; Pharmaceuticals; Biomanufacturing
University:
University of Waterloo
Program:
Globalink Research Award
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