Targeting Radiation-Induced CXCL12/CXCR4 Signaling and the Immune Microenvironment to Improve the Radio-Curability of Human Cancer

Medical images were collected from cervical tumors from mice undergoing cancer treatment using radiation to kill cancer cells and shrink tumors. The purpose is to discover new biological molecules and observe the immune system reacts during radiation treatment. These images will be analyzed by MATLAB, which is a computer platform. MATLAB will perform a couple of operations on an image to extract useful information from the image, such as the location and number of biological molecules and immune cells that appear during radiation therapy. By conducting the project, the project organization will gain a deeper understanding of new biological molecules that occur during radiotherapy and enhance the cure rate of radiotherapy.

Faculty Supervisor:

Hermann Eberl;Mohammad Kohandel

Student:

Partner:

Princess Margaret Cancer Centre

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology

University:

University of Guelph

Program: