The Predictive Relationship between fMRI and Polysomnography in Major Depressive Disorder

There has been extensive research on Major Depressive Disorder (MDD) and functional magnetic resonance imaging (fMRI), and MDD and polysomnography (PSG). However there has yet to be a link between these two experimental measures, leaving a gap in the literature. We hypothesize that by analyzing the results to the tests in conjunction detailed patient profiles can be created, therefore combating the issue of symptom variability. There will also be the addition of a probiotic supplement in order to increase the specificity of the study. Once this issue is fixed the movement towards clinical use can begin, which is the goal of the experiment. The hope is that the information provided by the study will create a concrete model to diagnose those with MDD and enhance treatment options.

Faculty Supervisor:

Roumen Milev

Student:

Partner:

Lallemand Health Solutions Inc (Montreal, QC)

Discipline:

Life Sciences

Sector:

Agriculture; Manufacturing; Professional, scientific and technical services

University:

Queen's University

Program: