Understanding Stress Signaling in Childhood Cancers: reactive oxidant species (ROS) signaling pathways

The Sorensen laboratory-based Childhood Cancer Research Program is specifically focused on elucidating the genetic and biological determinants of the metastatic process in childhood cancer.
Metastatic disease remains the single most dominant driver of adverse outcome in most childhood cancers, particularly in childhood sarcomas. There are two basic strategies in the program for
studying metastatic disease in childhood cancers. The first is to focus on cell stress signaling. Emerging evidence indicates that adaptation to prototypical forms of cell stress plays a major role in
tumor cell selection and metastasis

Faculty Supervisor:

Poul Sorensen

Student:

Partner:

Team Finn Foundation;BC Cancer Agency

Discipline:

Life Sciences

Sector:

Other services (except public administration)

University:

The University of British Columbia

Program: