Utilisant des outils modernes impliquant la génétique, la microscopie confocale et la biologie moléculaire, notre programme de recherche vise la découverte de composants de l’immunité innée conservés dans toutes les espèces. Les agents pathogènes sécrètent des protéines effectrices, également appelées facteurs de virulence, pour supprimer l’immunité. L’issue de l’infection (résistance ou maladie) dépendra de la […]

Inflammatory bowel disease (IBD) is a chronic condition affecting the gastrointestinal (GI) tract, characterised by periods of remission and flare-ups. The two main types of IBD are Crohn’s disease (CD), which can affect any part of the GI tract, and ulcerative colitis, which affects the colon. Predicting flare-ups and choosing the best treatments are major […]

Nearly 90% of drug candidates fail during the drug design and development process, resulting in exorbitant costs to bring a new drug to market. Our technology, LigandQI, addresses the critical shortcomings in current computational drug design programs by leveraging ab initio quantum chemistry to quantify ligand-receptor interactions with unprecedented accuracy. Unlike traditional methods, our program […]

Climate change is changing the distribution of mosquitoes, allowing them to become established in new places, potentially resulting in increased risk of mosquito-borne disease. The recent arrival of the invasive northern house mosquito, Culex pipiens, to Alberta is one such example. This mosquito, a major pest species found natively in Europe, is considered among the […]

Le travail agricole comporte certaines contraintes contextuelles relatives, entre autres, à l’économie, aux conditions climatiques et à l’environnement. Ces contraintes de travail engendrent un stress intense chez les propriétaires d’entreprises agricoles. En effet, selon une étude canadienne publiée en 2016, près de 60 % d’entre eux était à risque de vivre de la détresse psychologique. […]

A fertility app is proposed to help couples assess their risk of infertility, create personalized behavior change programs, and track fertility-related biomarkers. Personal, health, and lifestyle information will be collected and synced with smart devices to monitor menstrual cycles, ovulation, stress levels, heart rate, sleep patterns, and physical activity. Data will be continuously analyzed by […]

One of the situations that the Forensic Science needs to address is to establish the identity of a human or an specimen from a biological sample. The contribution of this project will be to obtain an optimized method for extracting DNA from hairs with and without follicles and to generate allelic frequencies suitable for use […]

The proposed project aims to develop innovative cell culture collection and extraction kits designed to streamline and improve the process of collecting cell samples in research laboratories. By addressing the current challenges of manual sample collection, such as time consumption, variability, and error-prone methods, our kit will enhance the reliability and efficiency of biological and […]

Le projet de recherche proposé vise à développer un service de diagnostic de l’état sanitaire, de nettoyage et de certification des plants-mères utilisés pour la multiplication par bouturage dans les cultures de cannabis thérapeutique et récréatif. Les méthodes de culture et de multiplication des plants de cannabis couramment utilisées entrainent une accumulation de microorganismes et […]

Parkinson’s disease (PD), a devastating neurodegenerative condition, is becoming increasingly prevalent in our aging population, yet the events leading to neuron death remain unclear. Current treatments aim to alleviate symptoms, but none address the cause of neurodegeneration, leaving a cure for PD elusive. Disease progression is marked by significant neuron loss in the brain region […]

Oxidative stress and aging are the primary risk factors for Parkinson’s disease (PD). The protein Nrf2 is particularly important in fighting oxidation and the associated damage in the brain as it activates antioxidant enzymes. Nrf2 is regulated by another protein called Keap1. These two proteins can get damaged under excessive oxidative stress conditions and thus […]

The Client Success Story Campaign is designed to boost the marketing efforts of Penrose Partners by showcasing the real-world impact and success of their blockchain consultancy services. Through this project, the intern will gather and present detailed case studies and testimonials from clients who have benefited significantly from Penrose Partners’ expertise. This content will be […]